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Adenomatous Polyposis Syndromes

Familial adenomatous polyposis (FAP) and MYH-associated polyposis (MAP) are the two main causes of hereditary pre-cancerous colon polyps. Individuals with FAP or MAP are at increased risk for cancers of the digestive tract. Gardner syndrome and Turcot syndrome are variants of FAP.

Features of the condition

• Multiple colon, rectal or other gastrointestinal polyps
• Colorectal cancer
• Cancer of the small intestine, thyroid, and pancreas
• Childhood liver cancer (hepatoblastoma)

Risk Factors

• Personal or family history of the features above
• Relative with a known diagnosis of FAP or MAP

Genetic Tests

The following genetic tests may be appropriate based on your personal and/or family history:

• APC
• MYH

Schedule an Appointment

To speak with a board-certified genetic counselor about your risks for this disease:

• Schedule genetic counseling appointment online
• Or call 1-800-975-4819
• Send email

Learn More

National Cancer Institute (NCI)

Genereviews

Support Groups