Take our online questionnaire to find out if genetic counseling is appropriate for you.

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Clotting Disorders

Blood clots can lead to serious complications when not detected early or if they are left untreated. Most blood clots are not caused by genetic factors, however there are certain gene mutations that can cause an increased risk for serious blood clots and recurrent pregnancy loss.

Symptoms

• Unexplained recurrent pregnancy loss
• Blood clots
• Deep vein thrombosis (DVT) in legs
• Pulmonary embolism (PE) in the lungs

Causes/Risk Factors

• Abnormal blood clotting prior to age 50
• Blood clots in liver, brain or intestine
• Blood clots that occur without a clear cause
• Blood clots that happen more than once
• A history of frequent miscarriages
• Stroke at a young age
• A family history of abnormal blood clotting
• Genetic mutations (see below

Genetic Test

The following genetic tests may be appropriate based on your personal and/or family history:

• Factor V Leiden
  • F5
• MTHFR
  • MTHFR
• Prothrombin
  • F2
• Protein C, Protein S or Antithrombin 3
  • PROC
  • PROS1
  • SERPINC1
• Genetic variants for blood clotting

Schedule an Appointment

To speak with a board-certified genetic counselor about your risks for this disease:

• Schedule genetic counseling appointment online
• Or call 1-800-975-4819
• Send email

Learn More

Centers for Disease Control (CDC)

National Institutes of Health Genetics Home Reference(NIH/GHR)

Genereviews: factor V Leiden, prothrombin